Ventilatory response to exercise in patients with left-to-right shunts.

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Ventilatory response to exercise in patients with left-to-right shunts.

et al., 1957; Bruce and John, 1957; Swan, Marshall, and Wood, 1958; Stephens, Shafter, and Bliss, 1964), but some uncertainty remains about the conclusions. Since any attempt to understand the disability of such patients depends on these, we have attempted a further investigation into the changes occurring during exercise. This paper deals with the hemodynamics, and a following communication is...

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Hemodynamic and Ventilatory Effects of Exercise in the Upright Position in Patients with Left-to-right Shunts.

THE behavior of the pulmonary vascular resistance during exercise in patients with ventricular septal defect or patent ductus arteriosus influences the magnitude and direction of tlhe shunt of blood across the defect and also may provide clues concerning the genesis of the pulmonary hypertension often seen in large defects. In previous studies,1' 2 pulmonary artery wedge pressure had not been d...

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Left-to-Right Shunts

Contrary to the opinion of French pediatrician HenriLouis that isolated ventricular septal defects (VSDs) are universally well tolerated, the subsequent discoveries of Eisenmenger, Abbott, Wood, and others have taught us that the prognosis of left-to-right shunt lesions is not always benign. After more than a century of research, as pediatric cardiologists and congenital heart surgeons, we clai...

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The Identification of Right-to-Left Shunts

SEVERAL METHODS are now used in conjunction with cardiac catheterization for localizing and quantitating right-to-left shunts. These include the recording of indicator-dye concentration curves after selective intracardiac dye injection,14 the external recording of radioactivity following injection of radioactive materials,5 6 and the use of cardioangiograms or cineangiograms to picture the cour...

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Quantitation of left-to-right cardiac shunts with radionuclide angiography.

A quantitative radionuclide angiogram technique using an intravenous injection of technetium99m (Tc-99m) pertechnetate is described for quantitation of left-to-right shunts in the central circulation. Data analysis assumes exponential indicator clearance from normal cardiac chambers by dilution. A late prolongation of tracer disappearance compared to the initial clearance rate indicates an abno...

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ژورنال

عنوان ژورنال: Heart

سال: 1966

ISSN: 1355-6037

DOI: 10.1136/hrt.28.5.590